Antioxidant and α-Glucosidase Activities of BenzoicAcid Derivate from the Bark of Myristica fatua Houtt

Myrictica fatua Houtt widely used in Indonesian as one of the traditional medicinal plants. Cancer and diabetic mellitus (DM) type 2 are two degenerative diseases caused by the presence of excessive free radicals in the body. Antioxidant and anti-diabetic active compounds were needed to reduce the risk of the diseases. One of the chemical compound groups that can be used as antioxidant and antidiabetic is phenolic compound. Isolation of the methanolic extract of the bark of M. fatua Houtt using chromatography methods led to the isolation of phenolic compound. Methyl 3,4-dihydroxybenzoate showed antioxidant and antidiabetic activities through DPPH free radicals scavenger and αglucosidase inhibitions activities test showed IC50 value 7.96 and 7.68 ug / mL, respectively

Proceedings of the 3rd International Symposium on Applied Chemistry 2017 AIP Conf. Proc. 1904, 020027-1–020027-5


No. Arsip : LIPI-20200803