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2019 Antiradical activity and physico-chemical analysis of crackers from Cucurbita moschata and modified cassava flour Anastasia Wheni Indrianingsih,Vita Taufika Rosyida,Wuri Apriyana,Septi Nur Hayati,Khoirun Nisa,Cici Darsih,Annisa Kusumaningrum,Anastasia Wheni Indrianingsih,Vita Taufika Rosyida,Vita Taufika Rosyida,Wuri Apriyana,Vita Taufika Rosyida,Wuri Apriyana,Septi Nur Hayati,Vita Taufika Rosyida,Wuri Apriyana,Septi Nur Hayati,Khoirun Nisa,Vita Taufika Rosyida,Wuri Apriyana,Septi Nur Hayati,Khoirun Nisa,Cici Darsih,Vita Taufika Rosyida,Wuri Apriyana,Septi Nur Hayati,Khoirun Nisa,Cici Darsih,Annisa Kusumaningrum Pumpkin (Cucurbita moschata) is one of the food commodity plants that grow in Indonesia. There is an increasing demand for fibre rich food and food ingredients. This study aimed to evaluate the antioxidant activity, morphological structure, chemical and physicochemical properties of crackers (Indonesian name: Kerupuk) made from pumpkin flour and mocaf. In this study, pumpkin pulps were processed into flour and substituted at 14%, 28% and 42% (K1, K2 and K3, respectively) and combined with modified cassava (mocaf) flour in a composite flour crackers formulation. The control crackers comprised of 100% of mocaf flour (K4). The crackers were characterized using… Lihat
2019 Lactobacillus pentosus isolated from Muntingia calabura shows inhibition activity toward alpha-glucosidase and alpha-amylase in intra and extracellular level Andri Frediansyah, Suryani, Rifa Nurhayati, Miftakhussolikhah and J. Sholihah Lactobacillus pentosus is one of the most prevalence lactic acid bacterium which available in plant-based fermentation. Here, we reported that the cell extract and cell-free supernatant of L. pentosus strain TL 2.7, TL 5.8 and TL 7.8 isolated from Kersen (Muntingiacalabura L.) showed potential anti-diabetic properties by inhibition of alpha-glucosidase and alpha-amylase activity in vitro. All isolated also enhanced the antioxidant capacity through DPPH in vitro test. This initial study will be beneficial for screening and application of functional food with anti-diabetic properties. Lihat
2019 Optimization of Cellulose Isolation from Melaleuca leucadendron Twigs by Box-Behnken Design Dwi Joko Prasetyo,Roni Maryana,Tri Hadi Jatmiko,Hernawan,Satriyo Krido Wahono The production of Melaleuca leucadendron essential oil generates a lot of solid waste, since only under 2% take it out as the oil product. The solid waste contains cellulose as an important content which can be isolated by alkaline treatment of sodium hydroxide (NaOH). In this project, optimization of alkaline treatment of M. leucadendron twigs (MLT) waste was studied in order to obtain optimum isolated cellulose. The experiments were conducted at atmospheric pressure and boiling temperature. The 33 Box-Behnken design (BBD) was used to evaluate the effects of treatment time, solid loading and NaOH concentration. Quadratic model evaluation showed that… Lihat
2019 Transformation of Mordenite-Clinoptilolite Natural Zeolite at Different Calcination Temperatures Satriyo Krido Wahono,Dwi Joko Prasetyo,Tri Hadi Jatmiko,Andri Suwanto,Diah Pratiwi,Hernawan,Krasimir Vasilev Natural zeolite is one of prospective material with various applications. The material has low-cost provisioning and abundant availability in the world. Mordeniteclinoptilolite is one of the common types of natural zeolite; one of the deposits are located in Gunungkidul, Yogyakarta, Indonesia. For optimizing the utilization, some treatment is needed, calcination being one of the possible treatments. The dealuminated natural zeolite was used as the base material for understanding the transformation effect, then calcinated the zeolite in various temperature range between 400 °C and 1000 °C. Some characterization was conducted after the treatment, such as XRD, SEM-EDX, and BET to explore… Lihat
2019 [JURNAL TERINDEKS SCOPUS DAN ESCI]: In Vitro Study of the Combination of Doxorubicin, Curcuma xanthorrhiza, Brucea javanica, and Ficus septica as a Potential Novel Therapy for Metastatic Breast Cancer Ika Rahmawati Sutejo, Herwandhani Putri, Riris Istighfari Jenie, Edy Meiyanto, Sri Handayani Less optimized therapeutic effects constrain the use of doxorubicin as the main agent of chemotherapy for metastatic breast cancer, resistance and side effects. Therefore we need a combination of more than one chemopreventive agent which has different molecular targets to solve that problem. The aims of this study is to prove the inhibitory effect of ethanolic extract of rhizome of Curcuma xanthorrhiza (ECx), fruit of Brucea javanica (EBj), leave of Ficus septica (EFs) and doxorubicin (Dox) alone and its combination on migration and invasion of a highly metastatic 4T1 breast cancer cell line. Cytotoxic activity of single and combination treatment… Lihat
2019 Geographical and Hydrological Conditions Ai Jun pan, Wei bo Wang, xi wu zhou, Kai Li, Mingzhang Zeng - Lihat
2019 Application of 1H-NMR based metabolite fingerprinting and chemometrics for authentication of Curcuma longa adulterated with C. heyneana Anjar Windarsih,,Abdul Rohman; Respati Tri Swasono Curcuma longa is known to have many pharmacological activities. This rhizome has the rich content in curcuminoids which curcumin is the main active component. It is important to ensure the authenticity of C. longa to avoid adulteration because it is related to the quality, efficacy, and safety of the products. Other Curcuma species such as C. heyneana have the potential to be used as adulterant because of its lower price, its strong yellow color, and its wide availability. In this study, thin layer chromatography (TLC) method was used to determine curcumin content in pure and adulterated powder of C. longa… Lihat
2019 Nutritional Evaluation of Ulva sp. from Sepanjang Coast, Gunungkidul, Indonesia T H Jatmiko, D J Prasetyo, C. D. Poeloengasih, Hernawan, Y Khasanah Seaweed is a food ingredient that abundant availability and high nutritional content. The chemical composition of seaweed differs depending on geographical and seasons and the environmental factors. This present study aim is to evaluate the nutritional composition, including proximate and mineral analysis, of green algae Ulva sp. from Sepanjang coast for utilization in the future for functional food. The results of the nutritional analysis of Ulva sp. show that the dominant element in the proximate analysis of Ulva sp. was carbohydrate (49.09%). Moisture, ash, fat and protein content were 9.89%, 31.4%, 0.38%, and 9.24% respectively, while crude fiber was 3.68%.… Lihat
2019 Antibacterial Bioactivity of n-Hexane Extract from Mahogany (Swietenia humilis Zucc.) Seed and Its Fatty Acid Compound Identification AP Asmara, Hernawan,C Nuzlia, Roni Maryana An investigation of antimicrobial bioactivity followed by GCMS analysis for the fatty acid composition has been conducted to the crude n-hexane extract of Swietenia humilis Zucc. seed. The goal of this research to determine the inhibition zone diameter for antimicrobial activity and the percentage of fatty acid contained in the extract. The seed of S. humilis Zucc. have been extracted by soxhletation with n-hexane as the solvent. The extract has been tested through in vitro antimicrobial bioassay toward Staphylococcus aureus and Escherichia coli by paper disc diffusion method. The fatty acid composition has been identified by fatty acid methyl esters… Lihat
2019 Seed Selection Using Molecular Approach for Ex Situ Conservation of Critically Endangered Tree Species (Vatica bantamensis (Hassk.) Benth. & Hook. ex Miq.) in Java, Indonesia Yayan Wahyu Candra Kusuma,Siti Roosita Ariati,Rosniati Apriani Risna,,,,Chika Mitsuyuki, Yoshihisa Suyama, and Yuji Isagi Ex situ conservation is an important complementary strategy for in situ to conserve endangered plant species. However, the limited areas designated for ex situ conservation such as in botanic gardens have become a great challenge for conservation practitioners and scientists attempting to optimally conserve the genetic diversity of targeted plant species. Our study aimed to assess genetic diversity and structure of wild seedlings of Vatica bantamensis, an endemic and critically endangered dipterocarp from Java (Indonesia). We also estimated genetic differentiation between the wild seedlings and existing ex situ collection and evaluated the genetic diversity preserved in the ex situ collection.… Lihat